
The study’s findings were fascinating as both regular and diet soft drink intake resulted in higher salivary insulin levels. The study was carried out amongst fifteen healthy adults between 18 and 45 years, with no history of diabetes or abnormal blood sugar levels. The aim of the study was to look at how consuming certain beverages influenced four key elements:
- Aspartame excretion in saliva — aspartame is a common artificial sweetener
- Salivary insulin levels — insulin is a hormone that allows the body’s cells to use glucose for energy; problems with insulin levels and the body’s response to insulin can lead to diabetes
- Total protein (TP)
- Alpha-amylase (AMI) — this enzyme helps the body digest sugar.
In theory, diet soft drinks should not raise a person’s insulin levels as insulin is released after we eat carbohydrates that increases our blood sugar levels, so it’s normal to have greater insulin after drinking a regular soda, but the results of this study challenge that idea. Researchers during the study asked participants to consume several beverages – diet soft drinks, regular soft drinks, mineral water with artificial sweeteners, plain water with a small amount of added sucrose, and plain water – while blindfolded for data collection. Researchers then collected saliva samples from participants and analyzed them.

These results of the study indicates that diet soda still influences insulin levels, even though these artificially sweetened beverages are sugar-free and low-calorie. Insulin release is a very essential part of blood sugar regulation, cellular metabolism, and muscle growth but in high quantities, insulin levels can lead to complications including weight gain due to the promotion of excess fat deposition and increased cardiovascular risk due to hypertension and atherosclerosis. High and inappropriate long-term insulin exposure can lead to micro and macrovascular complications associated with the morbidity and mortality increase in diabetics including retinopathy, erectile dysfunction, neuropathy, kidney disease, myocardial infarction, and stroke.
As much as the research was small, further studies are needed and the public would benefit from awareness of potential long-term metabolic health consequences that may exist with artificial sugar use in diet beverages.
